216 E 7Th St, Wayne, NE 68787 | Phone: 402-375-2922 | Fax: 402-375-1552 | Hours: Mon-Fri: 9a.m.-6p.m. Sat: 9a.m.-1:30p.m. Sun: Closed

Welcome to U-Save Pharmacy of Wayne

We’re a locally owned pharmacy dedicated to the well-being of you and your family. Please let us know how we can best serve you.

Refill a Prescription

Subscribe to our newsletter for seasonal promotions, health news and savings.

The Pharmacy for You

Our expertly trained pharmacists and friendly staff pride themselves on making sure your pharmacy experience exceeds expectations.

Special Services


Free Delivery

Along with our mailing services, we offer free daily delivery to patients within the Wayne city limits. Contact us to schedule your delivery.


Durable Medical Equipment

We offer a wide range of medical equipment, including styling wraps and ankle and wrist braces by Mueller.



We offer a variety of vaccines to keep you healthy. Contact us to learn more about our immunizations.


Medication Synchronization

Sync your medication refills with us and receive ALL of your medications on a single day each month.


"Wanted to let you know how much I appreciate your help and knowledge. It is comforting to know that what ever question I may have or whatever task I may need you to find or acquire for me, you will do your best to accomplish it. "


"I want to thank you and any of the others who work at USave Pharmacy in Wayne, NE, and supported my getting prescriptions for the ones I left at home. You made my stay and work at Wayne State College much easier because of your commitment to support and willingness to go many miles beyond what might be needed in a day’s work. I had called other pharmacies and did not get the “yes, we can do this for you” attitude that you presented. Know that your kind and thorough action made a major difference in my effectiveness and my physical well being.. I will never forget your calm, gracious support."


"I called your pharmacy to get prescriptions for my daughter who went to camp and forgot her medications. You were SO helpful. Thank you for all you do. "


"U-Save is always such a pleasant place to come with friendly people and great customer service. Your kindness, caring and added personal touch put you above so many and we are very greatful."